Basic Information
VIS ID
TVIS10015078
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp4 precore/core protein
Start
2323
Orient
-
Integrated sequence
CTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTAT| |CAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAG
Host Sequence
Chromosome
chr13
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
91419632/90767378 (Hg38)
End
91419632/90767378 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1297/Upstream/536101; hsa-mir-1267/Downstream/583227;
Nearest TSS
ENST00000623511/Upstream/274091; ENST00000618596/Downstream/159219;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1403857, chr13-CpG: 49/Downstream/407617
Upstream sequence
CTGAAGCCTCATTATATCCAAACCTTCTCCTACAGCTCTAGAAGTTATTCCATATTGGGGAATAATTGATCTGCTCATACAGCAGTTTATGAGATCCTGC
Downstream sequence
TATTTTTAAAATCTATTTCTTATCTGACTCAAAACTTAATCTGATGACTTCTTGACAAATTATAACCCTTTTATAAGCTCATAGTCAAAAGTTAGTTTCT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate