ARHGEF10L _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015087
Fusion event
HBV-ARHGEF10L integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
836
Orient
+
Integrated sequence
TTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTA| |AACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAA
Host Sequence
Chromosome
chr1
Cytoband
p36.13
Reference genome
GRCh37/hg19
Start
17842327/17515831 (Hg38)
End
17842327/17515831 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
ARHGEF10L
miRNAs that regulate target gene
hsa-mir-324-5p
Nearest miRNA
hsa-mir-12136/Upstream/237856; hsa-mir-101-1/Downstream/1367371;
Nearest TSS
ENST00000473358/Upstream/76107; ENST00000482892/Downstream/24004;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/75850, chr1-CpG: 100/Downstream/23603
Nearby gene
ARHGEF10L(No orient, 24002)
Upstream sequence
tcctgggctcaagagatcctcccacctcagcctcctgagtaactgggagaacaggtgtgcaccaccatgcctggctaacttttgcacttttagtagagac
Downstream sequence
agggttctgcatgtggcccagcctggtcttgaactcctggactcaagagatctgcccgcctgagtcaaatgctgggattacaagtgtgagccactgcacc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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