VISDB Viral Integration Site DataBase

VIS ID

TVIS10015090

Fusion event

HBV-ANK3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

2204

Orient

+

Integrated sequence

TAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTT| |GTGGTTTCACATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCA

Chromosome

chr10

Cytoband

q21.2

Reference genome

Start

End

62130934/60371176 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-218-5p ; hsa-mir-8088 ; hsa-mir-598-5p ; hsa-mir-216b-3p ; hsa-mir-8485 ; hsa-mir-603 ; hsa-mir-503-5p ; hsa-mir-34a-5p

Nearest miRNA

hsa-mir-1265/Upstream/3066617; hsa-mir-107/Downstream/3001781;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/464140, chr10-CpG: 60/Downstream/361851

Upstream sequence

ATCATGTCCCATTAATTTTCAAAGCATTTCTATCTGTGCTCCCTACAATATCTGCCACACTTCTCAGTTTTCAAGACTCCTTCAATCTACACATCTGTCT

Downstream sequence

CATCTCTACCCTCTGCCCTGGTAGATGTGCCCCTTCATAAGATCTCcaaaagaagacatacgagtggccaacaaacatatgaaaaaacgctccacatcac