VISDB Viral Integration Site DataBase

VIS ID

TVIS10015091

Fusion event

HBV-AHDC1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein;HBVgp4 precore/core protein

Start

1826

Orient

-

Integrated sequence

AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA

Chromosome

chr1

Cytoband

p36.11

Reference genome

Start

End

27898444/27571933 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1207-5p ; hsa-mir-1233-5p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-1910-3p ; hsa-mir-2467-3p ; hsa-mir-28-5p ; hsa-mir-30b-3p ; hsa-mir-3139 ; hsa-mir-3184-5p ; hsa-mir-3612 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-423-5p ; hsa-mir-4688 ; hsa-mir-4722-5p ; hsa-mir-4728-5p ; hsa-mir-4763-3p ; hsa-mir-486-3p ; hsa-mir-650 ; hsa-mir-6511a-5p ; hsa-mir-6721-5p ; hsa-mir-6743-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6778-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6805-5p ; hsa-mir-6883-5p ; hsa-mir-708-5p ; hsa-mir-7106-5p

Nearest miRNA

hsa-mir-12136/Upstream/1017340; hsa-mir-101-1/Downstream/3167223;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/2920, chr1-CpG: 98/Downstream/3356

Upstream sequence

GCTAATGGCAGACACACACTCCGCCTGTTCTGGGGGGACTGTTGCCGTTGCTAGGAAACCAGCAGCCGCGTGAATGGAAATGGGTCAGTAAACCTGGGGA

Downstream sequence

GAGATAGTGTGACACTCGAACCACTGCAGCTGCTCCAGCCCACACCGAAATCCCTCCTCTTCAATATTTATCACTCCCACCTGGGCCCTCAGCTCCTGCC