Fusion event
HBV-TERT integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Integrated sequence
CCTCTATGTATCCCTCCTGTTGCTGTACCAAACCTTCGGACGGAAATTGCACCTGTATTCCCATCCCATCATCCTGGGCTTTCGGAAAATTCCTATGGGA| |GTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATG
End
1295891/1295776 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-4635/Upstream/232802; hsa-mir-10397/Downstream/13534;
Nearest cancer related gene
Upstream sequence
ACTGGTCCCCTCCAGACCTGGGGCCCCGGCACAACCGCAGGACAGCTGAGGACTTCCCAGGAATCCAGACTCCGGGTTGCTCAAGTTTGGATCTAAGGGG
Downstream sequence
TTAATCACCCACCGGGGCGGTCCCGTCGAGAAAGGGTGGGAAATGGAGCCAGGCGCTCCTGCTGGCCGCGCACCGGGCGCCTCACACCAGCCACAACGGC
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.