Basic Information
VIS ID
TVIS10015097
Fusion event
HBV-chr4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
2819
Orient
+
Integrated sequence
GTTAATCATTACTTCCAAACTAGACACTATTTACACACTCTATGGAAGGCGGGTATATTATATAAGAGAGAAACAACACATAGCGCCTCATTTTGTGGGT| |CACCATATTCTTGGGAACAAGATCTACAGCATGGGGCAGAATCTTTCCACCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCA
Host Sequence
Chromosome
chr4
Cytoband
p16.3
Reference genome
GRCh37/hg19
Start
765763/771975 (Hg38)
End
765763/771975 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-571/Upstream/421723; hsa-mir-12113/Downstream/1214409;
Nearest TSS
ENST00000502981/Upstream/3786; ENST00000504850/Downstream/9855;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/11975, chr4-CpG: 78/Downstream/9308
Nearby gene
PCGF3(No orient, 1335)
Upstream sequence
tagggttagggttagggttagggttagggttagggttagggttagggttagggttagggttaagggttagggttagggttagggttagggttagggttag
Downstream sequence
GCCCCTGAGGCCCACCAAATCCTCCCAAAGTAGATGTCCATATGGCTTCTAGTTTTTAAGGATAAAACTCCCTTGAGATGCACTGAGTCCCTCCTGAGGG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate