VISDB Viral Integration Site DataBase

VIS ID

TVIS10015110

Fusion event

HBV-EFCAB2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

2042

Orient

+

Integrated sequence

AGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCA| |TTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCCAGCG

Chromosome

chr1

Cytoband

q44

Reference genome

Start

End

245226299/245062997 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-431-5p ; hsa-mir-3976

Nearest miRNA

hsa-mir-101-1/Upstream/1716742; hsa-mir-3124/Downstream/2138970;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/91588, chr1-CpG: 323/Downstream/90248

Upstream sequence

ttggcctctgttacctgggtgtaggagagctggctagcaaatcattacatggatttaacaaacccaggtctacaattacctaatctagtcaaccctggct

Downstream sequence

tgcagaagacaccatcacagaacttagtgacaccagtgcctttctcaccagcctgatacccttggtgagcagtgcatctgagccctcccatggaacagaa