VISDB Viral Integration Site DataBase

VIS ID

TVIS10015111

Fusion event

HBV-EFCAB2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein

Start

1761

Orient

-

Integrated sequence

GGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTT| |AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTA

Chromosome

chr1

Cytoband

q44

Reference genome

Start

End

245226113/245062811 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-431-5p ; hsa-mir-3976

Nearest miRNA

hsa-mir-101-1/Upstream/1716556; hsa-mir-3124/Downstream/2139156;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/91402, chr1-CpG: 323/Downstream/90434

Upstream sequence

ccccttccccatccttgcccttttttggttgtagatgttaggcagcacctttgttggctccacatctgttttgctcctaagcgtgctatgttctattaac

Downstream sequence

catctccacctttccccgtgactccctcttcaatctgtctgctcattatatgaggcctcttaacttctgtgctcaaacaactctgcttggcctctgttac