Basic Information
VIS ID
TVIS10015115
Fusion event
HBV-chr13 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
2476
Orient
-
Integrated sequence
AGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTG| |GGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCA
Host Sequence
Chromosome
chr13
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
30606159/30032022 (Hg38)
End
30606159/30032022 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-2276/Upstream/5869518; hsa-mir-1267/Downstream/9632012;
Nearest TSS
ENST00000623511/Upstream/8222; ENST00000435044/Downstream/76846;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/181218, chr13-CpG: 48/Downstream/82836
Upstream sequence
cctccagaggatgcaggtttcaaggtgccatcttggaagcagagatcaaaccctccccagacaccaaactggccggcaccttgatctgggaatgtccagc
Downstream sequence
ctctagaactgtaaggaattattttctgatttttatgaattagccagtctgtggtattctgttatagagcacaaaatggactgaagacacctgagttccc
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate