Basic Information
VIS ID
TVIS10015116
Fusion event
HBV-chrY integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp4 precore/core protein
Start
2412
Orient
+
Integrated sequence
CCCTATCCTATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCG| |CCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCT
Host Sequence
Chromosome
chrY
Reference genome
GRCh37/hg19
Start
58846331/58846331 (Hg38)
End
58846331/58846331 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/45367065;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/1642908, None/Downstream
Upstream sequence
TTGAGTTGCTGCTCTTGGGAGCTTGAGTCCAAGCCAGCAGTTCCAGATTCCTTCTGAGGTTAGAGAGGCACCTTCAGAGAGTTGCGTTTAACAAAGATCT
Downstream sequence
tctccacactttccattccactctgtttgagtccattccattccagtccatttaattcaagggcattccattccattccattccattccatttcatatta
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate