Basic Information
VIS ID
TVIS10015117
Fusion event
HBV-chrY integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp1 Polymerase;HBVgp4 precore/core protein
Start
2421
Orient
+
Integrated sequence
ATCAACACTTCCGGAGACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGC| |AGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAAT
Host Sequence
Chromosome
chrY
Reference genome
End
58857118/58857118 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-12120/Upstream/45377852;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/1653695, None/Downstream
Upstream sequence
AAGGAGATGTTGTAGTATTGAGCACTGAAAAAACCACGTCTAAAGTATTCTCAAAATCTTTCAAAGTGCCAACTGTCTCCCTCTCTCAACCTCTCTGTGT
Downstream sequence
ttccatttcatattattccattccattcaattccattccagatgattccattccattctataccattgctctctgttccattccattccatctgtctcca
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate