VISDB Viral Integration Site DataBase

VIS ID

TVIS10015125

Fusion event

HBV-ZNF827 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

985

Orient

-

Integrated sequence

ATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAA| |AGTATGTCAACGAATTGTGGGTCTTTTGGGTTTTGCTGCCCCTTTTACACAATGTGGTTATCCTGCGTTGATGCCTTTGTATGCATGTATTCAATCTAAG

Chromosome

chr4

Cytoband

q31.21

Reference genome

Start

End

146707000/145785848 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-16-5p ; hsa-mir-218-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-1252-5p ; hsa-mir-6730-5p ; hsa-mir-5584-5p ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4311 ; hsa-mir-3180-5p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-4744 ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-144-3p ; hsa-mir-4789-3p ; hsa-mir-101-3p

Nearest miRNA

hsa-mir-12113/Upstream/2442313; hsa-mir-1305/Downstream/622735;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/24183, chr4-CpG: 161/Downstream/150334

Upstream sequence

ttatgagacaggttagttttaccctactgatgatctgttgttgccatggtaatcctgctcagtaccaacccgcaggttcagacattcggtgtatgtgctt

Downstream sequence

AATACTCTTGGTTACACATGTGCAGATTTAGCAACAATCCAGACACTAGCACTTTTCTCCATTTCTGTTATTAAAAGTATAAGCCTAGAATATTTCCAGG