Basic Information
VIS ID
TVIS10015129
Fusion event
HBV-chr17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
411
Orient
+
Integrated sequence
TTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTC| |ATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGG
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
81195074/83247305 (Hg38)
End
81195074/83247305 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10226/Upstream/578998;
Nearest TSS
ENST00000595228/Upstream/19584;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/29825, None/Downstream
Nearby gene
RPL23AP87(-6501) ;
Upstream sequence
ctagggctagggctagggtttagggttagggttagggttagggttagggttagggttaggttagggtgagggtgagggtgagggtgagggtgagggtgag
Downstream sequence
ggtgagggtttagggttggggttggggttggggttggggttggggttggggttagggttagggttagggttagggttagggttagggtgtgggtgtgggt
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate