Basic Information
VIS ID
TVIS10015131
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1664
Orient
-
Integrated sequence
TCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGA| |CTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAA
Host Sequence
Chromosome
chr8
Cytoband
p11.21
Reference genome
GRCh37/hg19
Start
42501862/42646719 (Hg38)
End
42501862/42646719 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/986211; hsa-mir-10400/Downstream/249478;
Nearest TSS
ENST00000518652/Upstream/100291; ENST00000531610/Downstream/50657;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/104667, chr8-CpG: 63/Downstream/196007
Nearby gene
CHRNB3
Upstream sequence
cttaaggcacttaggacagaatctggaaatggtaaatacttcaaaagtattagctgttaGCTATTAGCTATGACATTTGCTAACACTTAAAAAGTCCTTC
Downstream sequence
tggctcacgcctgtaatcccagcactttgggaggccgaggcgggcggatcacctgagattaggagttcgagaccagcctggccaacatggtgaaaccccg
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate