VISDB Viral Integration Site DataBase

VIS ID

TVIS10015135

Fusion event

HBV-ZNF827 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2

Start

240

Orient

+

Integrated sequence

GGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATA| |CCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCAC

Chromosome

chr4

Cytoband

q31.21

Reference genome

Start

End

146711539/145790387 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-16-5p ; hsa-mir-218-5p ; hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-3153 ; hsa-mir-1252-5p ; hsa-mir-6730-5p ; hsa-mir-5584-5p ; hsa-mir-6873-5p ; hsa-mir-6856-5p ; hsa-mir-6758-5p ; hsa-mir-4311 ; hsa-mir-3180-5p ; hsa-mir-525-5p ; hsa-mir-520a-5p ; hsa-mir-4744 ; hsa-mir-466 ; hsa-mir-4643 ; hsa-mir-144-3p ; hsa-mir-4789-3p ; hsa-mir-101-3p

Nearest miRNA

hsa-mir-12113/Upstream/2446852; hsa-mir-1305/Downstream/618196;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/28722, chr4-CpG: 161/Downstream/145795

Upstream sequence

gtgggcacctgtactcccagctactcaggaggctgaggcaggagaatggcatgaaccagggaggcagagcttgcagtgagccaagatagcgccactgcac

Downstream sequence

AAAATACTCTAATATTCTAGAAATACTCTGAGTTTAGAAAGTAAATCCAGACTTTCTAAAATACTAAAATTTTAATGTTAATTTACTCCTGAAATGTTGC