VISDB Viral Integration Site DataBase

VIS ID

TVIS10015137

Fusion event

HBV-VPS36 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp3 X protein

Start

1707

Orient

-

Integrated sequence

GCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATA| |CTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA

Chromosome

chr13

Cytoband

q14.3

Reference genome

Start

End

53011792/52437657 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-21-5p ; hsa-mir-4480 ; hsa-mir-496 ; hsa-mir-759 ; hsa-mir-186-5p ; hsa-let-7c-3p ; hsa-mir-4662a-5p ; hsa-mir-3177-5p ; hsa-mir-6867-5p ; hsa-mir-574-5p ; hsa-mir-4693-3p ; hsa-mir-125a-3p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-6882-5p

Nearest miRNA

hsa-mir-15a/Upstream/884990; hsa-mir-1267/Downstream/372393;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/31206, chr13-CpG: 91/Downstream/12363

Upstream sequence

AGCATAAAAAGTCTATGCCAAGTTTTGTGTACATTCTTTTATCAAGTCATCCAATTACTATACTTCATTAAATTTTAAATTTATGAAATAAAgccgggcg

Downstream sequence

cggtggctcatgcctgtaatcccagcactttgggaggctgaggcgggtggatcatgaggtcaggagatcaagaccatcctggctaacacggtgaaacccc