Basic Information
VIS ID
TVIS10015141
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
1922
Orient
+
Integrated sequence
TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA| |AGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAA
Host Sequence
Chromosome
chr8
Cytoband
p12
Reference genome
End
34782288/34924770 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/4967422; hsa-mir-10400/Downstream/6346278;
Upstream sequence
ACAAATATTGTGCTTTAAAACAAACAAAGCCACAATAACAAAAACAGAGTCAGAAGTTATGTGTCAGTGCCCAGCCTGCAATAACTGATGCTGAGACAGT
Downstream sequence
aattgcaataatctagctaagagattaggaaagcatgtagtaggcagtggcaatgtgaataaggatgaacgaacatgttgaagagactttcaaaaggtaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate