Basic Information
VIS ID
TVIS10015142
Fusion event
HBV-chr16 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp4 precore/core protein
Start
2347
Orient
-
Integrated sequence
ATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCCCTATCCTATCAACACTTCCGGAGACTACTGTTG| |TTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCTCGGGAATCTCA
Host Sequence
Chromosome
chr16
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
46416802/46382890 (Hg38)
End
46416802/46382890 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/12219217; hsa-mir-11401/Downstream/3909726;
Nearest TSS
ENST00000527434/Upstream/10596003; ENST00000569239/Downstream/201363;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/10280177, chr16-CpG: 124/Downstream/44568
Upstream sequence
atcatcaaatgaaattgaatggagtcatcgaatgtcatcgaattgaatcatcaccaaattgagtcgaatggaatcatcgaatggagtgaaatggaatcat
Downstream sequence
catcgaagggaatggaatagaatcatcgaattgactcgaaagaatcatcatcgaagggaattgaaaggaattatcaaatggaatacaagagaaacatcat
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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