Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015147
Fusion event
HBV-ABI3BP integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
1946
Orient
-
Integrated sequence
CTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTT| |ACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCTCAGCTCTGTATCGGGAAGCCTTAGAGTCTCCTGAGCATTGT
Host Sequence
Chromosome
chr3
Cytoband
q12.2
Reference genome
End
100565966/100847122 (Hg38)
Orient
+
Location type
Promoter
Target gene
Nearest miRNA
hsa-let-7g/Upstream/882724; hsa-mir-12124/Downstream/2676911;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/137297, chr3-CpG: 48/Downstream/665644
Upstream sequence
CTGAAACATTTGAAAGTGATTAAATATTTAACTCAATGATAGATTTTTAAATGTCACTATGACAGTAGTACTCTGCCCACATGTGCATAGGATTAATGAA
Downstream sequence
CCTGTCTACCTAAACACATTTTAATAAGAAAAAAACTACTCTCAAAAAAATTCACCAATAGGTATAATGCTATGATCTGAAGCATAAAGTAATTCTACTA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.