Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015149
Fusion event
HBV-ABI3BP integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp1 Polymerase;HBVgp2 pre-S1/pre-S2/S
Start
3148
Orient
+
Integrated sequence
GCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTACCCCGCTGTCTCCACC| |TTTGAGAAACACTCATCCTCAGGCCATGCAGTGG
Host Sequence
Chromosome
chr3
Cytoband
q12.2
Reference genome
End
100565895/100847051 (Hg38)
Orient
-
Location type
Promoter
Target gene
Nearest miRNA
hsa-let-7g/Upstream/882653; hsa-mir-12124/Downstream/2676982;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/137226, chr3-CpG: 48/Downstream/665715
Upstream sequence
GCACATGTAAGTGTGACATAAATCTGTACCCTTAAGCAATCATAATCTTATTTGAAAAAATCATAGGCAAAGACAATATGGCTTTCAAGAGTTGACATCT
Downstream sequence
ACTTCCTGCATACAATTTTAGGGTGGCATTTTTCTTTTTCTCCTAATATTTCCAGAATCTGTCACTTTGGGCCTGTCTACCTAAACACATTTTAATAAGA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.