Basic Information
VIS ID
TVIS10015150
Fusion event
HBV-chr3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S
Start
56
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTT| |CCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAAC
Host Sequence
Chromosome
chr3
Cytoband
q24
Reference genome
GRCh37/hg19
Start
144417689/144698847 (Hg38)
End
144417689/144698847 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/10260941; hsa-mir-1224/Downstream/6867029;
Nearest TSS
ENST00000440867/Upstream/725239; ENST00000482351/Downstream/1241065;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/725410, chr3-CpG: 97/Downstream/1461796
Upstream sequence
CTTTGAAAAGAAAGCTGCTGATGTCTGAGTTTTATGGGAGTCCTAGCCAGCTGTTTAAGTGTTCTTCTTAACACTTAAGTATATTTTGTAACAGAAGAAA
Downstream sequence
TTATCTTTGCaaaatatatttataataatgtatagttattagtatttaataaaaCAGTTTGGGTAGAACAAAACAGTATTTTAAGGTATTTGTCTTTAAT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate