VISDB Viral Integration Site DataBase

VIS ID

TVIS10015152

Fusion event

HBV-CLPTM1L integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

1852

Orient

+

Integrated sequence

GATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTT| |CATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTC

Chromosome

chr5

Cytoband

p15.33

Reference genome

Start

End

1319152/1319037 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-22-3p ; hsa-mir-5093 ; hsa-mir-203a-3p ; hsa-mir-3622b-3p ; hsa-mir-3622a-3p ; hsa-mir-3688-3p ; hsa-mir-4694-3p ; hsa-mir-6856-3p

Nearest miRNA

hsa-mir-4457/Upstream/9660; hsa-mir-10397/Downstream/191725;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/23182, chr5-CpG: 18/Downstream/15925

Upstream sequence

TCCGGGCGGACCCGGGGGTCTGGGCCGCGCTTCCCCGCCCGCGCGCCGCTCGCGCTCCCAGGGTGCAGGGACGCCAGCGAGGGCCCCAGCGGAGAGAGGT

Downstream sequence

CAGGTCTGGAGCCATTAACACAGAGCCTGAGTACAGCACAGTTTCAGGCACGCCCCGGGCCACCTGCGAGGACTTGGGAGCCACTTGAAGGGCTCACAGT