Basic Information
VIS ID
TVIS10015156
Fusion event
HBV-STMND1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1685
Orient
-
Integrated sequence
CTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGT| |CAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTG
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
17118628/17118397 (Hg38)
End
17118628/17118397 (Hg38)
Orient
-
Location type
Intronic
Target gene
STMND1
Nearest miRNA
hsa-mir-3691/Upstream/976773; hsa-mir-10398/Downstream/1453387;
Nearest TSS
ENST00000381078/Upstream/7902; ENST00000366215/Downstream/9541;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/16089, chr6-CpG: 149/Downstream/162111
Upstream sequence
ACAAAGGAGAACCAGTGAGTTCTTTGTTTTTCTACTAAAATAGTTAATTATTCTCATCTATTTCAATCAGAGTAAAATAACCAGATTCTCTAGAGCTTTT
Downstream sequence
ttactagtttctgtattttctaaatttactacagtaactatcacttttataatcaaaaagaaGCACAACATGGTTTTTAAACAATCCCCAATATTCTCCA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate