VISDB Viral Integration Site DataBase

VIS ID

TVIS10015157

Fusion event

HBV-PDE4D integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase

Start

2618

Orient

+

Integrated sequence

AATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGA| |AAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACCAAATATTTACCATTGGATAAGGGTATTAAACCTTATTATCCAGAACATCT

Chromosome

chr5

Cytoband

q12.1

Reference genome

Start

End

59252107/59956280 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-340-5p ; hsa-mir-7-5p ; hsa-mir-103a-3p ; hsa-mir-19b-3p ; hsa-mir-18a-5p ; hsa-mir-16-5p ; hsa-mir-3148 ; hsa-mir-4668-5p ; hsa-mir-4457 ; hsa-mir-5590-3p ; hsa-mir-142-5p ; hsa-mir-6783-5p ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-6835-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-7158-3p ; hsa-mir-548ac ; hsa-mir-31-3p ; hsa-mir-302f ; hsa-mir-4760-3p ; hsa-mir-4282 ; hsa-mir-18b-5p ; hsa-mir-4735-3p ; hsa-mir-4439 ; hsa-mir-3136-5p ; hsa-mir-6857-3p ; hsa-mir-6855-3p ; hsa-mir-4513 ; hsa-mir-4502 ; hsa-mir-4682 ; hsa-mir-1324 ; hsa-mir-4422 ; hsa-mir-3611 ; hsa-mir-4325 ; hsa-mir-4266 ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-6080 ; hsa-mir-6888-5p ; hsa-mir-3120-3p ; hsa-mir-3646 ; hsa-mir-424-3p ; hsa-mir-199a-5p ; hsa-mir-139-5p

Nearest miRNA

hsa-mir-10397/Upstream/252577; hsa-mir-103a-1/Downstream/12213187;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/62599, chr5-CpG: 87/Downstream/743267

Upstream sequence

AGGGAAGTCAAAGCTCTTTGCCTCCAATTAACTAGTAACTAAGACCGAATCATCTGCCTGTGAGGAAAAGAGTCCCACAAAACTCAGCTAGGGAGCACTC

Downstream sequence

AACACAGCCCCTTCCCCCTTGCAGTTCCTCACAGGAACTCAGACTCTCTGGCTGCCCCTACCTTGTCTATCAGTCCAATGCTAGCAACTTGATGGGGTTT