GRM7 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015161
Fusion event
HBV-GRM7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
1363
Orient
+
Integrated sequence
CGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATA| |TACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCT
Host Sequence
Chromosome
chr3
Cytoband
p26.1
Reference genome
GRCh37/hg19
Start
7194528/7152841 (Hg38)
End
7194528/7152841 (Hg38)
Orient
-
Location type
Intronic
Target gene
GRM7
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-34c-5p
Nearest miRNA
hsa-mir-4790/Upstream/1902586; hsa-let-7g/Downstream/3127510;
Nearest TSS
ENST00000440867/Upstream/258819; ENST00000461677/Downstream/145736;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/289887, chr3-CpG: 42/Downstream/1348674
Upstream sequence
ctgcactgttccttctttacacattagttccccgttactgtccaaagtggatgtgttttgttggccttgcctaaggggtatattcctgccattgctgcca
Downstream sequence
GCTAAAACagtcagatattcatgttcctagcctgccttgaagctagggtacagtcattaattcagtcttggctaatcagacatacctatcaggaatgaaa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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