Basic Information
VIS ID
TVIS10015163
Fusion event
HBV-LINC02217 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S
Start
31
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAAACTCTGCAAG| |ATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTC
Host Sequence
Chromosome
chr5
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
17412236/17412127 (Hg38)
End
17412236/17412127 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02217
Nearest miRNA
hsa-mir-10397/Upstream/256135; hsa-mir-103a-1/Downstream/14523975;
Nearest TSS
ENST00000502646/Upstream/7981; ENST00000505844/Downstream/24610;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/57498, chr5-CpG: 30/Downstream/79221
Upstream sequence
CACTCACCCTGCACGTGACAGGGACACCCGGGGACCACGCCTCACTCCCTGCATAAGCCAGGGGCAGATTGTGACCTCATCTGAAGTCAGAGAACAGCAA
Downstream sequence
TACACGCTCTGAGCTATTTCAAAAAATACAGCACTTAAGCCAATTGAGCTGTAGTCAGGGCAACACAGGCATGAATAACATGAAGGTAGATTTTAGTAGA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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