Basic Information
VIS ID
TVIS10015164
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1761
Orient
-
Integrated sequence
GGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTT| |AAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTA
Host Sequence
Chromosome
chr7
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
109739518/110099461 (Hg38)
End
109739518/110099461 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/7627930; hsa-mir-10399/Downstream/4553884;
Nearest TSS
ENST00000635602/Upstream/502295; ENST00000464835/Downstream/435293;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/1528999, chr7-CpG: 68/Downstream/1462562
Nearby gene
ZNF462
Upstream sequence
TTGAGGCAAGATGCACACCTGTTCCCACTCCCAGTTGTAGTGTCATTAAATGGATTTTTACTCTTTATATTCCTACCACCTTTCACGTTGAGGGCGAGTA
Downstream sequence
acagccaacattatactgaatggggaaggttgaaagcattctccccctgagaactggaagaagacaaggaagcccacttttaccactttattcaacatag
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate