Basic Information
VIS ID
TVIS10015166
Fusion event
HBV-chr10 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1905
Orient
-
Integrated sequence
CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG| |GACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCTAGATACCGCCT
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
42394337/41845870 (Hg38)
End
42394337/41845870 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/6204618; hsa-mir-107/Downstream/1151693;
Nearest TSS
ENST00000439456/Upstream/3392689; ENST00000442306/Downstream/339469;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/2902764, chr10-CpG: 184/Downstream/265163
Upstream sequence
attgaatggaattgaatggaatcgtcatcgaatgaattgaatgcaatcatcgaatggtctcgaatggaatcatcatcaaatggaaaggaatgaaatcatc
Downstream sequence
gcatagaatcgaatggaattatcattgaatggactcgaatggaatcaacatcaaacggagtcaaacggaattatcgaatggaatcgaaGAGAATCATCAA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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