Basic Information
VIS ID
TVIS10015167
Fusion event
HBV-chr12 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
2120
Orient
+
Integrated sequence
AAGCCTTAGAGTCTCCTGAGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGG| |TGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCT
Host Sequence
Chromosome
chr12
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
34372612/34219677 (Hg38)
End
34372612/34219677 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/8345598; hsa-let-7i/Downstream/8104023;
Nearest TSS
ENST00000382841/Upstream/824; ENST00000553138/Downstream/4096901;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/308, chr12-CpG: 30/Downstream/115998
Nearby gene
DUX4L27(-9876) ;
Upstream sequence
atcctggttcccggcgcatggcgggacatgcccctcctgaggcagagcggcccgccggaggggacggcagaggaccgcctatccaaggccaacAAagcca
Downstream sequence
agcacatacacaaaatgtctgaacctgcggttcctctcgtactgagcaggattaccatggtagcaacacatgggcaacaacacaaggggaacgcaaacag
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate