VISDB Viral Integration Site DataBase

VIS ID

TVIS10015168

Fusion event

HBV-GLS2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2

Start

203

Orient

-

Integrated sequence

CTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACA| |GGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTT

Chromosome

chr12

Cytoband

q13.3

Reference genome

Start

End

56868896/56475112 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-16-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/2137798; hsa-let-7i/Downstream/719392;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/6468, chr12-CpG: 93/Downstream/12505

Nearest cancer related gene

GLS2(TSG, No orient, 0)

Upstream sequence

GGGACTTTCTCTTCCGGCCTCTTCTGGTTACCTTCTTTTCCTTGAGATAATAGCCGATGGCATAATTCCGATCCCCTGTTTCCTTCTCTGACTGGAATCT

Downstream sequence

GAAGCAAACACCCAATTTAGTACTTGAAGTTGGAGGAGTGGGTGTTGGGAGAAGGGGAAAAATTACCTTCCCTGGAGAGACAGAACTACATCACACCACA