VISDB Viral Integration Site DataBase

VIS ID

TVIS10015171

Fusion event

HBV-CYSLTR2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2

Start

723

Orient

-

Integrated sequence

GGCTTTCGGAAAATTCCTATGGGAGTGGGCCTCAGCCCGTTTCTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACT| |GTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTT

Chromosome

chr13

Cytoband

q14.2

Reference genome

Start

End

49243132/48668996 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-6873-3p ; hsa-mir-6868-3p ; hsa-mir-627-3p ; hsa-mir-1237-3p ; hsa-mir-6832-3p ; hsa-mir-500a-5p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-1248 ; hsa-mir-6867-3p ; hsa-mir-5196-5p ; hsa-mir-4747-5p ; hsa-mir-107 ; hsa-mir-103a-3p ; hsa-mir-605-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-3162-3p ; hsa-mir-9500 ; hsa-mir-3714

Nearest miRNA

hsa-mir-2276/Upstream/4472796; hsa-mir-1267/Downstream/1327419;

Nearest TSS

Nearest CpG islands

None/Target, chr13-CpG: 551/Upstream/135669, chr13-CpG: 132/Downstream/306690

Upstream sequence

atagtttccagcttcatctatctccctgcaaaggacatgaactcattcttttttatggctgcgtagtattccatagtgtacatgtgtcacattttcttta

Downstream sequence

tccagtctatcattgatgggcatttgggtttgttccaagtctttcctattgtgaaaaatgctgcaataaacatgtgtgtgaatgtgtctttatagtagaa