Basic Information
VIS ID
TVIS10015174
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein
Start
1735
Orient
-
Integrated sequence
AATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGG| |GAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTG
Host Sequence
Chromosome
chr7
Cytoband
p14.1
Reference genome
GRCh37/hg19
Start
42769958/42730359 (Hg38)
End
42769958/42730359 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1183/Upstream/5810927; hsa-mir-10399/Downstream/420536;
Nearest TSS
ENST00000635602/Upstream/23912; ENST00000432845/Downstream/114079;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/236675, chr7-CpG: 74/Downstream/181258
Nearby gene
HOOK3
Upstream sequence
taacaagcagtaactgtccctactgtcccaatgctgagatactgtgatcaaggaaaagactcccccactatggctgagatccagcccccacttggagaga
Downstream sequence
gcaccactgcactccagcctgggtcacagagtgaagccttgtctcaaaaaaaaaaaaaaaaagaaaagaaaaaagaaaaTTTTCAAAATGAATGTATCCA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate