Fusion event
HBV-chr1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S
Integrated sequence
AATTCCACA| |ACCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCT
End
64616823/64151140 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12132/Upstream/824156; hsa-mir-101-1/Downstream/428707;
Upstream sequence
CAAACTGTTTTTTGgttaagcttctggcaggaaacacatggcacaagccgatagactaagggaaatgttataatgtaattatttagggaggcattggcag
Downstream sequence
aattaggagaaaccattaaggaaaggtgcgagacctggggctaacatgaatgggaggtattaccatcctagatcagttaccttaccttgcagaatatagc
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.