Fusion event
HBV-chr1 integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp1 Polymerase
Integrated sequence
ATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGA| |CATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACC
End
64616819/64151136 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-12132/Upstream/824152; hsa-mir-101-1/Downstream/428711;
Upstream sequence
GTAACAAACTGTTTTTTGgttaagcttctggcaggaaacacatggcacaagccgatagactaagggaaatgttataatgtaattatttagggaggcattg
Downstream sequence
gcagaattaggagaaaccattaaggaaaggtgcgagacctggggctaacatgaatgggaggtattaccatcctagatcagttaccttaccttgcagaata
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.