Basic Information
VIS ID
TVIS10015177
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp1 Polymerase
Start
2568
Orient
+
Integrated sequence
ATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAATCCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGA| |CATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAAGAAGATTGCAATTGATTATGCCTGCCAGGTTTTATCCAAAGGTTACC
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
End
64616819/64151136 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-12132/Upstream/824152; hsa-mir-101-1/Downstream/428711;
Upstream sequence
GTAACAAACTGTTTTTTGgttaagcttctggcaggaaacacatggcacaagccgatagactaagggaaatgttataatgtaattatttagggaggcattg
Downstream sequence
gcagaattaggagaaaccattaaggaaaggtgcgagacctggggctaacatgaatgggaggtattaccatcctagatcagttaccttaccttgcagaata
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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