VISDB Viral Integration Site DataBase

VIS ID

TVIS10015180

Fusion event

HBV-XKR4 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp4 precore/core protein

Start

2138

Orient

+

Integrated sequence

AGCATTGTTCACCTCACCATACTGCACTCAGGCAAGCAATTCTTTGCTGGGGGGAACTAATGACTCTAGCTACCTGGGTGGGTGTTAATTTGGAAGATCC| |AGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCACATTTCTTGTCTCACTTTTGGAAGA

Chromosome

chr8

Cytoband

q12.1

Reference genome

Start

End

56264215/55351655 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-4468 ; hsa-mir-3650 ; hsa-mir-1193 ; hsa-mir-298 ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-2392 ; hsa-mir-7851-3p ; hsa-mir-490-3p ; hsa-mir-4668-5p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-5692b ; hsa-mir-5692c ; hsa-mir-3163 ; hsa-mir-369-3p ; hsa-mir-4282 ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-335-3p ; hsa-mir-5096 ; hsa-mir-5006-3p ; hsa-mir-4755-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-623 ; hsa-mir-642b-5p ; hsa-mir-3920 ; hsa-mir-4637 ; hsa-mir-33a-3p ; hsa-mir-409-3p ; hsa-mir-6858-3p ; hsa-mir-550b-2-5p ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-1227-3p ; hsa-mir-3683 ; hsa-mir-1273c ; hsa-mir-210-5p ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6810-3p ; hsa-mir-6801-3p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-6769a-3p ; hsa-mir-508-5p ; hsa-mir-196a-3p ; hsa-mir-4790-3p ; hsa-mir-382-3p ; hsa-mir-338-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-3616-3p ; hsa-mir-383-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-4779 ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-2053 ; hsa-mir-6868-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-3667-3p ; hsa-mir-6741-3p ; hsa-mir-670-3p ; hsa-mir-3655 ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-4698 ; hsa-mir-8063 ; hsa-mir-3613-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-5698 ; hsa-mir-8057 ; hsa-mir-5001-3p ; hsa-mir-891a-3p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-24-3p ; hsa-mir-564 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-2276-3p ; hsa-mir-5693 ; hsa-mir-6890-3p ; hsa-mir-6796-3p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-3147 ; hsa-mir-4425 ; hsa-mir-4707-3p ; hsa-mir-520g-3p ; hsa-mir-520h ; hsa-mir-6778-3p

Nearest miRNA

hsa-mir-124-1/Upstream/12455380; hsa-mir-10400/Downstream/6363133;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/248531, chr8-CpG: 22/Downstream/97641

Upstream sequence

gataactggaaatatacatattcttctattctcacaacagtctggtgatataggaattattattatgtccattttacagatgaggaaactaaggtaaaga

Downstream sequence

tgtctgtgctttcttcacaagatagccaactcttacatcttcacacagccaacatcactggcccccctgatcaaagccagcatcttttctcacctggatt