VISDB Viral Integration Site DataBase

VIS ID

TVIS10015181

Fusion event

HBV-chr9 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp3 X protein

Start

1620

Orient

-

Integrated sequence

ACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCAC| |CGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGT

Chromosome

chr9

Cytoband

q21.2

Reference genome

Start

End

79323010/76708094 (Hg38)

Orient

+

Location type

Promoter

Target gene

ECPAS ; PRUNE2

miRNAs that regulate target gene

hsa-mir-130b-3p ; hsa-mir-155-5p ; hsa-mir-196a-5p ; hsa-mir-93-5p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-16-5p ; hsa-mir-769-5p ; hsa-mir-320a ; hsa-mir-185-5p ; hsa-mir-382-3p ; hsa-mir-770-5p ; hsa-mir-377-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-4671-3p ; hsa-mir-593-5p ; hsa-mir-6124 ; hsa-mir-4733-3p ; hsa-mir-3148 ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-570-5p ; hsa-mir-548ba ; hsa-mir-548ai ; hsa-mir-548ag ; hsa-mir-4796-3p ; hsa-mir-548m ; hsa-mir-196b-5p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-130a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-19a-3p

Nearest miRNA

hsa-mir-101-2/Upstream/5898010; hsa-let-7a-1/Downstream/7261654;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/248449, chr9-CpG: 75/Downstream/197793

Upstream sequence

tttaatggatgtgtacgtgtttgtgtgtgtgtgtgtataaaaatttatcaaaaagtatattttcactatgtgtaggttattatatgtaagttatacctct

Downstream sequence

TTGAGGACTGAAAGTGACAGCAAGAGAGCTGATTTTGCCTGATTTAATGCAGATTTCCTGATGTTCAGATGCAACCAGAGAAGACAGTTCCTGGTCACTC