Basic Information
VIS ID
TVIS10015187
Fusion event
HBV-chr6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
2214
Orient
+
Integrated sequence
GGTGGGTGTTAATTTGGAAGATCCAGCGTCTAGAGACCTAGTAGTCAGTTATGTCAACACTAATATGGGCCTAAAGTTCAGGCAACTCTTGTGGTTTCAC| |ATTTCTTGTCTCACTTTTGGAAGAGAAACAGTTATAGAGTATTTGGTGTCTTTCGGAGTGTGGATTCGCACTCCTCCAGCTTATAGACCACCAAATGCCC
Host Sequence
Chromosome
chr6
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
54875590/55010792 (Hg38)
End
54875590/55010792 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10398/Upstream/1733721; hsa-mir-10524/Downstream/2379340;
Nearest TSS
ENST00000381078/Upstream/164021; ENST00000615358/Downstream/95668;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/163557, chr6-CpG: 15/Downstream/163580
Upstream sequence
GAGGAAGTGCGGGGGGTTCGCGGCGCGGGGAGGGTGATCCCGGGAGGACTTGCGCGGCGCGTGGGGCGGGGCACAGATGCTCCCCGGCCTGGCTCCGAGT
Downstream sequence
CAACACAAGTTCTCCCTCCTGTTTGACCGTTTTGAGAAACTGCTTGTGAAGTGGTGCTTTTATATCAAGCATCATCAGACTTCACTTCCATTTGTAAGTC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate