Basic Information
VIS ID
TVIS10015189
Fusion event
HBV-chr14 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp3 X protein;HBVgp4 precore/core protein
Start
1823
Orient
-
Integrated sequence
TTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAA
Host Sequence
Chromosome
chr14
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
41005116/40535911 (Hg38)
End
41005116/40535911 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/3583520; hsa-mir-1185-1/Downstream/7225084;
Nearest TSS
ENST00000550708/Upstream/148353; ENST00000515218/Downstream/418987;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1102909, chr14-CpG: 47/Downstream/1070744
Upstream sequence
ttgtttttatttctctcataccttgaagtgtgacattaatttcttcatttgaaaaattatctgtccttttgatgtaggcatttatgctataaactttcct
Downstream sequence
TGCAGTaaaattcttaacataatcctagcataccaaatctaacagcacatcagaaagataattccaatgataaagtgggctttatttcagggatgcaagg
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate