Basic Information
VIS ID
TVIS10015190
Fusion event
HBV-chr7 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S
Start
21
Orient
+
Integrated sequence
AATTCCACAACCTTCCACCAA| |ACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGT
Host Sequence
Chromosome
chr7
Cytoband
q33
Reference genome
GRCh37/hg19
Start
134071791/134387039 (Hg38)
End
134071791/134387039 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10525/Upstream/1096051; hsa-mir-10399/Downstream/819955;
Nearest TSS
ENST00000635602/Upstream/36248; ENST00000475559/Downstream/45377;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/69809, chr7-CpG: 93/Downstream/71324
Nearby gene
STK32C
Upstream sequence
TGTCTTAAAGAGAAATAGAGATTATTGTCAGAGTCCAGATAATTGCGTTTATATGGGTAGAGAGATCTCTTCATTAATTCCAAAACTGTGTAGCtaaaat
Downstream sequence
gccattacttttatggcaaaaacaacaattacttttggaccaacctaatggaaacattgtgagcactgttgaaatgaccacaaaggatttagaatattca
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate