Basic Information
VIS ID
TVIS10015191
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
1304
Orient
-
Integrated sequence
TGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGC| |AGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGA
Host Sequence
Chromosome
chr8
Cytoband
q11.23
Reference genome
GRCh37/hg19
Start
53342019/52429459 (Hg38)
End
53342019/52429459 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/9533184; hsa-mir-10400/Downstream/9285329;
Nearest TSS
ENST00000518652/Upstream/19514; ENST00000331251/Downstream/31500;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/529707, chr8-CpG: 117/Downstream/135525
Nearby gene
ST18(No orient, 19579)
Upstream sequence
tgatatgctgaggtgaacttttttagcattaatcctggttggtgttctttgagcttcttagatctgtagtttggtgtctgacattaatttaggaaaattc
Downstream sequence
ttcctgcactcgtgtcttggcacagaaggcgattataaatgtttgttggatgtgccaggcattgtaacaagcagtgtaaatatagagatgaataaaatga
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate