VISDB Viral Integration Site DataBase

VIS ID

TVIS10015194

Fusion event

HBV-GCLM integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2012

PubMed ID

Virus name

HBV

Reference genome

Region type

HBVgp1 Polymerase;HBVgp3 X protein

Start

1564

Orient

-

Integrated sequence

CTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTC| |TCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGA

Chromosome

chr1

Cytoband

p22.1

Reference genome

Start

End

94360364/93894808 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-15a-5p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-5587-5p ; hsa-mir-6801-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-4781-3p ; hsa-mir-433-5p

Nearest miRNA

hsa-mir-101-1/Upstream/47897; hsa-mir-11399/Downstream/648894;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/15542, chr1-CpG: 122/Downstream/14005

Upstream sequence

TGGTTACTATTTGGTTTTACCTAGAAGTGAAAATAAAATCATGATATCACTACTAAATTAAATATAATACCAAAAGTAGAAAGCAATAAGCAATAAAATA

Downstream sequence

ACTTAATTTTAGAACATATGAAAAATCACAATCCACAGTGATTAAAGTTTACAAAATACTTTTACATTAATATCTTTATTAATATATGCTTTTCTAACCC