Fusion event
HBV-TERT integration
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Region type
HBVgp1 Polymerase;HBVgp2 pre-S1/pre-S2/S
Integrated sequence
CCAGCAATCCTCTGGGATTCTTTCCCGACCACCAGTTGGATCCAGCCTTCAGAGCAAACACCGCAAATCCAGATTGGGACTTCAATCCCAACAAGGACAC| |CTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAGGCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATA
End
1295400/1295285 (Hg38)
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-4635/Upstream/232311; hsa-mir-10397/Downstream/14025;
Nearest cancer related gene
Upstream sequence
GCTCCGGGCGGACCCGGGGGTCTGGGCCGCGCTTCCCCGCCCGCGCGCCGCTCGCGCTCCCAGGGTGCAGGGACGCCAGCGAGGGCCCCAGCGGAGAGAG
Downstream sequence
CCCCGACAGCGCAGCTGCTCCGGGCGGACCCGGGGGTCTGGGCCGCGCTTCCCCGCCCGCGCGCCGCTCGCGCTCCCAGGGTGCAGGGACGCCAGCGAGG
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.