Basic Information
VIS ID
TVIS10015198
Fusion event
HBV-chr18 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp1 Polymerase;HBVgp2 pre-S2/S;HBVgp2
Start
765
Orient
-
Integrated sequence
CTCCTGGCTCAGTTTACTAGTGCCATTTGTTCAGTGGTTCGTAGGGCTTTCCCCCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCA| |AGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTA
Host Sequence
Chromosome
chr18
Cytoband
q12.3
Reference genome
End
38204577/40624613 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-2/Upstream/947834; hsa-mir-122/Downstream/4345469;
Upstream sequence
ATGAGAACAAATCCAACCACTAAATATTAAAGAGAAAAAAAGATTTCAAGAAATGGAGTAGAAATGACTTTAGTTAGAATTCTTGCCTTGGCCAATAATT
Downstream sequence
AGAGCAAGATGTTTTGCCCCAATGACGGTGATTAAAAGTATATCCTTTTTTTTGCCCTGAATATTAAACATGTTAGGATATGCATTTTACTTTAATGTGA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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