Basic Information
VIS ID
TVIS10015202
Fusion event
HBV-chr1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
1847
Orient
+
Integrated sequence
GAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTC| |TTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTA
Host Sequence
Chromosome
chr1
Cytoband
p22.2
Reference genome
End
90826072/90360514 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/4002827; hsa-mir-11399/Downstream/3486318;
Upstream sequence
GGGCCGGAGGATTGTGCTATTGTCTCTTCACACTGGACTTTCAGGGTTGGTTTGGCTCAGGTGATGGGAGGGTGAGCGACCCTTCGTTACCTTCATCAGT
Downstream sequence
AACTGGCCTCCCCAAGGAGGCAGACATAAGAGAAGGAGTCTTCTAATGGAGGAGGACCACTCTGACAATCAGGAACTCTTTGCCTCCCAGAACCCTAGAG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate