hsa-mir-422a _LIHC.png
TERT _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10015208
Fusion event
HBV-TERT integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp4 precore/core protein
Start
1894
Orient
+
Integrated sequence
ATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGC| |TTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTACGAGATCTTCT
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
End
1296259/1296144 (Hg38)
Orient
-
Location type
Promoter
Target gene
Nearest miRNA
hsa-mir-4635/Upstream/233170; hsa-mir-10397/Downstream/13166;
Nearest CpG islands
Nearest cancer related gene
TERT(OG, No orient, 0)
Upstream sequence
ACCAGGCACTGGGCCACCAGCGCGCGGAAAGCCGCCGGGTCCCCGCGCTGCACCAGCCGCCAGCCCTGGGGCCCCAGGCGCCGCACGAACGTGGCCAGCG
Downstream sequence
CGAGAAACTTCTGGGTCTCCCGAGGCCTTGCAGGGATGCTGTAGCTGAGGTCGGCAAACACTGAAATGCTAACAAACGCAACCTTAAATGTAACCTTTCC
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate