Basic Information
VIS ID
TVIS10015214
Fusion event
HBV-LINC00333 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1874
Orient
+
Integrated sequence
CTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTC| |CAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTT
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
84766274/84192139 (Hg38)
End
84766274/84192139 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC00333
Nearest miRNA
hsa-mir-1297/Upstream/6494023; hsa-mir-1267/Downstream/3426526;
Nearest TSS
ENST00000623511/Upstream/309746; ENST00000446314/Downstream/370225;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/312377, chr13-CpG: 121/Downstream/3479175
Upstream sequence
TTTCTGTTTTTAGACACTAGTAAATTCACTTTATTCTTTGGAAGAGCAGAAAGGATTTCAGGATCCTGAGAGGAAAATTGCTAGAACCATTCATGCCGAG
Downstream sequence
CACTTTTGCAGCCTTCTCCTATCTTGAGAGCATGTGCAACAAGATCAGTGAGGGCCCAAGGCAACAACCTTAGGATGATAAACATGGGCCAAGCTTCACA
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate