Basic Information
VIS ID
TVIS10015215
Fusion event
HBV-LINC00333 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase
Start
1303
Orient
-
Integrated sequence
CTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCG| |CAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGG
Host Sequence
Chromosome
chr13
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
84766393/84192258 (Hg38)
End
84766393/84192258 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC00333
Nearest miRNA
hsa-mir-1297/Upstream/6494142; hsa-mir-1267/Downstream/3426407;
Nearest TSS
ENST00000623511/Upstream/309865; ENST00000446314/Downstream/370106;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/312496, chr13-CpG: 121/Downstream/3479056
Upstream sequence
TATCTTGAGAGCATGTGCAACAAGATCAGTGAGGGCCCAAGGCAACAACCTTAGGATGATAAACATGGGCCAAGCTTCACATTGAGAAGTAGACTCCCTC
Downstream sequence
TCTGTGATGAAACACTACAGTCCATGCTGCAAATTAGACACCAGTGAGTCATCTCAATAGTGTTAAGCTTCCAGCTATGTATGAACAGTCTTAAGTAGTG
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate