Basic Information
VIS ID
TVIS10015216
Fusion event
HBV-LOC105372047 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp1 Polymerase;HBVgp3 X protein
Start
1613
Orient
-
Integrated sequence
ACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGG| |AGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAA
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
27949309/30369343 (Hg38)
End
27949309/30369343 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105372047
Nearest miRNA
hsa-mir-1-2/Upstream/70383; hsa-mir-122/Downstream/5222394;
Nearest TSS
ENST00000575820/Upstream/841040; ENST00000583089/Downstream/343932;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/2191132, chr18-CpG: 128/Downstream/672180
Upstream sequence
aaaaaaaaaaaaaaagctgggcatggtggcacactggcatacgcctgtagtcctagctacctgaaaggctgaggtgagaggatcacttgaacccaggagg
Downstream sequence
tcaaggctgcagtgaaccatgatggcactcctgcaccccagcctgggtgacagagcaagactctgcttcaaaaaaactgaatgaataaatgaataaataa
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
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