Basic Information
VIS ID
TVIS10015217
Fusion event
HBV-LOC105372047 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Region type
HBVgp3 X protein
Start
1810
Orient
+
Integrated sequence
CAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCA| |GCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACAT
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
End
27949501/30369535 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1-2/Upstream/70575; hsa-mir-122/Downstream/5222202;
Upstream sequence
ataaataaaagaaaagaaaaaaagcctctttacattttgtttcagtggaattgaggtcagtctctcccctccagttgcaatagtcttgactcctactaca
Downstream sequence
actatcttgaataaagtctttctcgcagattttaacaggcgtccagtgcaacatttctttgataaagcttcctaatatccattttgtccctggtgttccg
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate