Basic Information
VIS ID
TVIS10015220
Fusion event
HBV-chr8 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2012
PubMed ID
22634754
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Region type
HBVgp4 precore/core protein
Start
1878
Orient
+
Integrated sequence
GAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAG| |CTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTT
Host Sequence
Chromosome
chr8
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
59068667/58156108 (Hg38)
End
59068667/58156108 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/15259833; hsa-mir-10400/Downstream/3558680;
Nearest TSS
ENST00000518652/Upstream/49814; ENST00000638450/Downstream/255156;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/9253, chr8-CpG: 53/Downstream/255139
Nearby gene
FAM110B(No orient, 6389)
Upstream sequence
tataaaatatcaaagtacacaaaatatgtattgtatactgtacataaaatatcaaagtacaccaaatatatattatttactgtacataaaatatcaaaca
Downstream sequence
ACCCTCATATTTGTCCCAAAAGACAATGAGTAGCATACTCCTTTTCTCAGCCAAAATACAAAAACTTACCCTTTATGCGAAAATATATCCTTGGGGTAGT
Reference
Sung, W. K., et al. Genome-wide survey of recurrent HBV integration in hepatocellular carcinoma. Nat Genet,2012, 44(7): 765-769.
Curate